Gene interactions and pathways from curated databases and text-mining

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CCR4 — IL18

Text-mined interactions from Literome

Ito et al., J Immunol 2003 (Encephalomyelitis, Autoimmune, Experimental) : Additionally, IL-12 selectively enhanced mRNA expression of CCR5, whereas IL-18 selectively enhanced the expression of CCR4 and CCR7, and CCR4 and CCR5 were coexpressed on the surface of T cells cocultured with IL-12 and IL-18
Rodriguez-Galán et al., J Immunol 2005 : Additionally, IL-18 in combination with IL-2 induces CCR4 ( Th2 associated ) and CCR5 ( Th1 associated ) gene expression