Gene interactions and pathways from curated databases and text-mining

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FASLG — MYC

Text-mined interactions from Literome

Brunner et al., J Biol Chem 2000 : Expression of Fas ligand in activated T cells is regulated by c-Myc
Kasibhatla et al., Curr Biol 2000 : A ` non-canonical ' DNA binding element mediates the response of the Fas-ligand promoter to c-Myc ... The FasL promoter can be driven by c-Myc overexpression, and functional inhibitors of Myc and its binding partner, Max, inhibit the transcriptional activity of the FasL promoter [ 9,10 ]
Tani et al., FEBS Lett 2001 (Brain Neoplasms...) : Proteasome inhibitors induce Fas mediated apoptosis by c-Myc accumulation and subsequent induction of FasL message in human glioma cells
Wiener et al., Exp Cell Res 2004 (Carcinoma, Non-Small-Cell Lung...) : Our results revealed that inhibition of c-Myc/Max did not substantially reduce basal levels of Fas ligand promoter activity, nor did overexpression of c-Myc significantly induce promoter activity ... Our results revealed that inhibition of c-Myc/Max did not substantially reduce basal levels of Fas ligand promoter activity, nor did overexpression of c-Myc significantly induce promoter activity
Duan et al., Dig Dis Sci 2010 (Bile Duct Neoplasms...) : The effects of MAPK-ERK cascade inhibitor and c-Myc inhibition by siRNA on 67-kDa laminin receptor induced FasL expression were determined
Wang et al., Oncogene 1998 : Thus, c-Myc plays a fundamental role in the regulation of the expression of FasL , but not Fas and IL-2