Zhao et al., Cell Immunol 2005
(MAP Kinase Signaling System) :
Although gAd partially increased cAMP concentration and PKA activity, it directly reduced leptin induced ERK1/2 and p38 MAPK phosphorylation thus inhibiting TNF-alpha production
Otero et al., Life Sci 2007
:
Phosphatidylinositol 3-kinase, MEK-1 and p38 mediate leptin/interferon-gamma synergistic NOS type II induction in chondrocytes
Ben-Eliezer et al., Endocrine 2007
:
It was found that leptin increased phosphorylation of ERK1/2, p38 , and STAT3 in a time- and dose dependent manner
Cha et al., BMB Rep 2012
:
We also showed that p38 mitogen activated protein kinase signaling was involved in leptin expression induced by HER2