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HGF — IL6

Text-mined interactions from Literome

Okada et al., J Hypertens 2000 (Cardiovascular Diseases) : Neutralizing antibodies against tumor necrosis factor (TNF)-alpha, interleukin (IL)-1beta and IL-6 inhibited the HGF production in THP-1 cells and VSMCs that was induced by the coculture conditioned medium
de Jong et al., Scand J Gastroenterol 2001 (Breast Neoplasms...) : Recombinant human interleukin-6 induces hepatocyte growth factor production in cancer patients ... It is suggested that IL-6 initiates hepatocyte growth factor (HGF) synthesis ... The aim of the study was to examine the effect of exogenously administered recombinant human IL-6 ( rhIL-6 ), in doses of 0.5, 1.0, 2.5, 5, 10 and 20 micrograms/kg/day, on HGF serum levels in humans
Naruishi et al., J Dent Res 2001 (Gingivitis) : Interleukin-6 (IL-6) binds to human gingival fibroblasts (HGF) in the presence of a soluble form of IL-6 receptor ( sIL-6R )
Kariv et al., Liver Int 2003 : Triiodothyronine and interleukin-6 (IL-6) induce expression of HGF in an immortalized rat hepatic stellate cell line
Matsumoto et al., Biochem Biophys Res Commun 1992 : Up-regulation of hepatocyte growth factor gene expression by interleukin-1 in human skin fibroblasts
Takami et al., Biochem Biophys Res Commun 2004 : HGF production is induced by the activation of protein kinase A and protein kinase C-mediated pathways, interleukin (IL)-1 , tumor necrosis factor (TNF)-alpha, and epidermal growth factor (EGF) in mesenchymal cells
Yokoyama et al., Oral Microbiol Immunol 2005 : Stimulation of HGF with VEGF resulted in production of IL-6 and IL-8 in a dose dependent manner
Beldi et al., Gastroenterology 2008 (Disease Models, Animal) : The effects of extracellular ATP on vascular endothelial growth factor ( VEGF ), hepatocyte growth factor (HGF), and interleukin-6 responses were determined in vivo and in vitro
Onimaru et al., Int J Oncol 2008 (Leukemia-Lymphoma, Adult T-Cell) : The levels of HGF and/or IL-6 which induces the production of HGF by stromal cells, were elevated in the supernatant of short-term cultured cells from certain patients with acute or chronic disease
Lee et al., Cell Signal 2009 : Hepatocyte growth factor induces delayed STAT3 phosphorylation through interleukin-6 expression
Knowles et al., Clin Cancer Res 2009 (Carcinoma, Squamous Cell...) : c-Met TKIs blocked HGF induced signaling, interleukin-8 release, and wound healing
Kamimoto et al., Int J Mol Med 2009 (Acute Disease...) : Furthermore, Sn-PP partially restored the HGF mediated decrease in plasma IL-6 levels, while it inhibited the HGF stimulated increase in plasma IL-10 levels
Schmeding et al., Transplantation 2010 (Fatty Liver) : Analysis of liver enzymes, histology ( hematoxylin-eosin and periodic acid Schiff stain ), immunostaining ( terminal deoxynucleotide transferase- mediated dUTP nick-end labeling, hypoxyprobe, and tumor necrosis factor-alpha ), and reverse transcriptase-polymerase chain reaction of cytokine messenger RNA ( interleukin-1 , interleukin-6, hypoxia induced factor-1 alpha, vascular endothelial growth factor, and hepatocyte growth factor ) were performed at defined time points ( 2, 4.5, 24, 48 hr, and 7 days postoperatively )
Thatch et al., J Pediatr Surg 2010 (Cholestasis, Intrahepatic...) : Hepatocyte growth factor induced less interleukin-6 ( P < .011 ) and tumor necrosis factor alpha ( P < .01 ) expression
Chen et al., Stem Cells Dev 2011 (Acute Kidney Injury...) : Real-time polymerase chain reaction result showed that HGF-hucMSCs also inhibited caspase-3 and interleukin-1ß mRNA expression in injured renal tissues
Wang et al., Hum Gene Ther 2013 (Disease Models, Animal...) : MSCs-HGF could reduce secretion and expression of proinflammatory cytokines, including tumor necrosis factor-a, interferon-?, interleukin (IL)-6, and intercellular adhesion molecule-1, and increase the expression of antiinflammatory cytokine IL-10
Bazin et al., J Immunol 1987 (Ascites...) : The HGF activity was not mediated by interleukin 1 because the two activities could be completely separated by gel filtration
Sugiyama et al., Infect Immun 1996 : Lipoteichoic acid and interleukin 1 stimulate synergistically production of hepatocyte growth factor ( scatter factor ) in human gingival fibroblasts in culture
Liu et al., Am J Physiol 1996 : We found simultaneous induction of both HGF and its receptor gene expression by interleukin-6 (IL-6) in primary cultured rat glomerular mesangial cells
Gohda et al., J Cell Physiol 1998 (Leukemia) : Granulocyte colony stimulating factor ( G-CSF ), granulocyte/macrophage colony stimulating factor ( GM-CSF ), interleukin (IL)-5 and IL-6 had no effect on HGF/SF production in the 2 leukemia cell lines ... Granulocyte colony stimulating factor ( G-CSF ), granulocyte/macrophage colony stimulating factor ( GM-CSF ), interleukin (IL)-5 and IL-6 had no effect on HGF/SF production in the 2 leukemia cell lines
Kent et al., Infect Immun 1998 : The purpose of this study was to investigate the effect of lipopolysaccharide (LPS) and inflammatory cytokines on regulation of interleukin-6 (IL-6) production by human gingival fibroblasts (HGF)
Bamba et al., Biochem Biophys Res Commun 1998 (Peptic Ulcer...) : Among various potential stimulants tested, interleukin-1 beta (IL-1 beta) dramatically increased PGE2 production and significantly stimulated HGF production
Miyazaki et al., Biochem Biophys Res Commun 1998 : Increased hepatocyte growth factor production by aging human fibroblasts mainly due to autocrine stimulation by interleukin-1 ... The increased production of HGF by aging fibroblasts from human embryonic lung tissue is mainly due to autocrine stimulation by interleukin-1
Hou et al., J Periodontal Res 1998 (Periodontal Diseases...) : These data show that HGF express PAR-1 and suggest that PAR-1 activation stimulates increased NF-IL-6 and IL-6 gene expression and IL-6 secretion by HGF in vitro
Nakano et al., Hypertension 1998 (Cardiovascular Diseases...) : Interestingly, transforming growth factor ( TGF ) -ss significantly decreased HGF secretion from EC, whereas interleukin 6 stimulated immunoreactive HGF secretion