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FGF2 — SLC22A3

Text-mined interactions from Literome

Morabito et al., Dev Biol 2001 : We confirmed FGF stimulation and TGFbeta inhibition of epicardial EMT in organ culture
Tanaka et al., Molecular vision 2004 (Eye Injuries, Penetrating) : To examine the role of fibroblast growth factor 2 (FGF2) in regulating lens cell proliferation and epithelial-mesenchymal transition (EMT) in response to injury ... Endogenous FGF2 is required for increased cell proliferation but not essential for EMT during the lens response to injury
Ko et al., Invest Ophthalmol Vis Sci 2005 : FGF-2 directly mediates corneal EMT through the action of PI 3-kinase, which acts on posttranscriptional regulation by affecting the stability of type I collagen RNA
Katoh et al., Curr Pharm Biotechnol 2011 : Because FGF , Hedgehog, TGFß, and non-canonical WNT signals synergistically induce EMT regulators, such as Snail ( SNAI1 ), Slug ( SNAI2 ), TWIST, and ZEB2 ( SIP1 ), tumor-stromal interaction at the invasion front aids cancer stem cells to acquire more malignant phenotype
Shirakihara et al., EMBO J 2011 (Neoplasm Invasiveness...) : Consequently, normal epithelial cells that have undergone EMT as a result of combined TGF-ß and FGF-2 stimulation promoted the invasion of cancer cells ... Thus, TGF-ß and FGF-2 may cooperate with each other and may regulate EMT of various kinds of cells in cancer microenvironment during cancer progression
Martínez-Morales et al., J Cell Biol 2011 (MAP Kinase Signaling System) : Furthermore, we show that FGF and RA signaling control EMT in part through the modulation of elements of the bone morphogenetic protein and Wnt signaling pathways
Lee et al., Exp Eye Res 2012 (Corneal Diseases...) : Furthermore, we will discuss the role of inflammation on FGF-2 mediated EMT ... Interleukin-1ß (IL-1ß) greatly upregulates FGF-2 production in CECs, thus leading to FGF-2 mediated EMT ; the whole spectrum of the injury mediated inflammation ( IL-1ß pathway ) and the subsequent EMT process ( FGF-2 pathway ) will be briefly discussed
Masola et al., J Biol Chem 2012 (Fibrosis...) : FGF-2 induces EMT in PTECs ... In human kidney 2 (HK2) PTEC cultures, although FGF-2 induces EMT in the wild-type clone, it is ineffective in heparanase silenced cells ... In conclusion, heparanase plays a role in the tubular-interstitial compartment favoring the FGF-2 dependent EMT of tubular cells
Savagner et al., Mol Biol Cell 1994 (Urinary Bladder Neoplasms) : Therefore, EMT can be induced through different FGF receptors, but EMT may also regulate FGF receptor expression itself