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NPTX1 — RELA
Text-mined interactions from Literome
Roccaro et al., Blood 2008
(Waldenstrom Macroglobulinemia) :
We found that
NPI-0052 inhibited proliferation and induced apoptosis in WM cells, and that the combination of NPI-0052 and bortezomib induced synergistic cytotoxicity in WM cells,
leading to inhibition of nuclear translocation of
p65NF-kappaB and synergistic induction of caspases-3, -8, and -9 and PARP cleavage
Baritaki et al., J Immunol 2008
(Neoplasms) :
NPI-0052 induced inhibition of
NF-kappaB activity was involved in TRAIL sensitization as corroborated by the use of the NF-kappaB inhibitor dehydroxymethylepoxyquinomicin