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CSF2 — EGF
Text-mined interactions from Literome
Vinante et al., Blood 1999
:
Granulocyte-macrophage
colony stimulating factor induces expression of heparin binding
epidermal growth factor-like growth factor/diphtheria toxin receptor and sensitivity to diphtheria toxin in human neutrophils
Demetri et al., Blood 1989
(Mesothelioma) :
These data indicate that ( a ) normal human mesothelial cells spontaneously express detectable levels of M-CSF mRNA in culture ; ( b )
EGF is an essential cofactor for optimal induction of G-CSF and
GM-CSF expression ; ( c ) exposure of normal mesothelial cells to inflammatory mediators such as LPS and TNF
increases the levels of transcripts for CSFs and IL-1 beta ; and ( d ) as compared with normal human mesothelial cells, some cell lines of human malignant mesothelioma exhibit aberrant gene expression for multiple cytokines, including G-CSF, GM-CSF, IL-1 beta, and IL-6