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EZH2 — RELA
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Min et al., Nat Med 2010
(Neoplasm Invasiveness...) :
Moreover, we report that epigenetic silencing of DAB2IP is a key mechanism by which the polycomb-group protein histone-lysine N-methyltransferase
EZH2 activates Ras and
NF-kappaB and triggers metastasis
Lee et al., Mol Cell 2011
(Breast Neoplasms) :
This function of
EZH2 is independent of its histone methyltransferase activity but
requires the physical interaction with
RelA/RelB to promote the expression of NF-?B targets