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HLF — TGFB1
Text-mined interactions from Literome
Hashimoto et al., Am J Respir Crit Care Med 2001
:
The results showed that : ( 1 ) TGF-beta1 caused the phenotypic modulation of HLF to myofibroblasts in a dose- and a time dependent manner ; ( 2 )
TGF-beta1 induced increases in c-Jun-NH2- terminal kinase (JNK), p38 MAPK, and extracellular signal regulated kinase ( Erk ) phosphorylation and activity ; ( 3 ) the inhibitors CEP-1347, SB 203580, and PD 98059 attenuated TGF-beta1 induced JNK, p38 MAPK, and Erk activity, respectively ; and ( 4 ) CEP-1347, but not SB 203580 or PD 98059,
attenuated the TGF-beta1 induced phenotypic modulation of
HLF to myofibroblasts in a dose dependent manner
Hu et al., Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 2006
:
[ p38/ERK signal pathways regulating the expression of type I collagen and activity of MMP-2 in
TGF-beta1 stimulated
HLF-02 cells ]