Gene interactions and pathways from curated databases and text-mining

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TCF7 — TGFB1

Text-mined interactions from Literome

Prasad et al., J Am Coll Nutr 1999 (Neoplasms) : The proposed mechanisms for these effects include inhibition of protein kinase C activity, prostaglandin E1-stimulated adenylate cyclase activity, expression of c-myc, H-ras, and a transcription factor ( E2F ), and induction of transforming growth factor-beta and p21 genes
Palcy et al., J Bone Miner Res 2000 : Our data emphasize the role of the AP-1 transcription factor in TGF-beta1 and BMP-2 signaling and highlight the importance of this transcription factor family in the expression of OB genes
Peinado et al., J Biol Chem 2003 (MAP Kinase Signaling System) : Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines : mechanisms for epithelial mesenchymal transitions
Funaba et al., J Biol Chem 2003 : Transcriptional activation of mouse mast cell Protease-7 by activin and transforming growth factor-beta is inhibited by microphthalmia associated transcription factor
Singh et al., American journal of physiology. Renal physiology 2004 : Similarly, TGF-beta1 and hexosamines led to nonadditive increases in phosphorylation of the cAMP responsive element binding transcription factor
Lee et al., J Exp Clin Cancer Res 2003 : Effect of ets related transcription factor ( ERT ) on transforming growth factor ( TGF)-beta type II receptor gene expression in human cancer cell lines
Sieczkiewicz et al., Microvasc Res 2003 : TGF-beta 1 induces expression of the myogenic transcription factor myf-5 and the cyclin dependent kinase inhibitor p27 ; we show that these signaling pathways are disrupted in the DNT beta RII bearing pericytes
Kim et al., Int J Biochem Cell Biol 2004 (MAP Kinase Signaling System) : We also found that TGF-beta1 reduces microphthalmia associated transcription factor ( MITF ) promoter activity and decreased MITF, tyrosinase, tyrosinase related protein-1 (TRP-1), and TRP-2 protein production
Murakami et al., Cell Signal 2006 : Microphthalmia associated transcription factor ( MITF ), a member of the basic helix-loop-helix leucine zipper family of tissue-specific transcription factors predominantly expressed in mast cells, melanocytes and osteoclasts, also stimulated PAI-1 gene transcription, and TGF-beta1 did not increase PAI-1 mRNA levels in mast cells from mi/mi mice expressing dominant negative MITF
Chiarpotto et al., Biofactors 2005 (Fibrosis) : In fact, 4-hydroxy-2,3-nonenal ( HNE ), the major aldehydic product of lipid peroxidation, is able to induce TGFbeta1 expression and synthesis, and activation of activator protein-1 (AP-1) transcription factor
Zhang et al., Am J Pathol 2006 : In contrast inhibition of p38 MAP kinase inhibited de novo TGF-beta1 protein synthesis but did not influence TGF-beta1 mRNA expression or activation of either transcription factor
Ohtsuki et al., Mol Cell Biol 1992 : Transforming growth factor-beta 1 ( TGF-beta 1 ) rapidly increases the expression of junB transcription factor and plasminogen activator inhibitor-1 ( PAI-1 ) and prevents the cell cycle dependent phosphorylation of the RB retinoblastoma susceptibility gene product during late G1 phase in Mv1Lu lung epithelial cells
Kaimori et al., J Biol Chem 2007 : We also show that in hepatocytes in the EMT state, TGF-beta1 induces the snail-1 transcription factor and activates the Smad2/3 pathway
Herrmann et al., Biochim Biophys Acta 2007 : In the present study we found that during cellular activation and transdifferentiation the SRF transcription factor is up-regulated by transforming growth factor-beta , accumulated in the nucleus, and exhibited increased DNA binding activity
Lee et al., American journal of physiology. Renal physiology 2008 : Sevoflurane and TGF-beta1 caused the nuclear translocation of the SMAD3 transcription factor in HK-2 cells
Chen et al., Immunol Res 2008 (Bacterial Infections) : In the mouse, the differentiation of this new lineage is initiated by TGFbeta-1 and IL-6 and IL-21, which activate Stat3 and induce the expression of the transcription factor retinoic acid related orphan receptor ( RORgammat )
Clifford et al., J Biol Chem 2008 : Finally, we demonstrate that TGFbeta(1) regulates TCF by modifying beta-catenin phosphorylation via regulation of glycogen synthase kinase 3beta
Herzinger et al., Oncogene 1995 : We have studied the effect of TGF-beta 1 on protein binding to a transcription factor E2F consensus element in extracts from early passage human keratinocytes ( HFKs ) and a permanent human keratinocyte cell line ( HaCaT )
Alevizopoulos et al., J Biol Chem 1996 : Antagonistic regulation of a proline-rich transcription factor by transforming growth factor beta and tumor necrosis factor alpha