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CCL2 — VCAM1
Text-mined interactions from Literome
Maus et al., Am J Respir Crit Care Med 2002
(Disease Models, Animal...) :
In
response to
JE/MCP-1 plus E. coli LPS, we observed additional engagement of CD11a and
CD106 for enhanced alveolar monocyte transmigration
Lin et al., PloS one 2012
(Osteoarthritis) :
Here, we investigated the intracellular signaling pathways involved in
CCL2 induced
vascular cell adhesion molecule-1 ( VCAM-1 ) expression in human OA synovial fibroblasts ( OASFs ) ... Stimulation of OASFs with
CCL2 induced
VCAM-1 expression ...
CCL2 mediated
VCAM-1 expression was attenuated by CCR2 inhibitor ( RS102895 ), PKCd inhibitor ( rottlerin ), p38MAPK inhibitor ( SB203580 ), and AP-1 inhibitors ( curcumin and tanshinone IIA ) ... The
CCL2 induced
VCAM-1 expression promoted monocytes adhesion to human OASFs
Del Papa et al., Arthritis Rheum 1996
(Wegener Granulomatosis) :
We found that AECA IgG from WG patients do not display any significant cytotoxicity but are able to up-regulate the expression of E-selectin, intercellular adhesion molecule 1 and
vascular cell adhesion molecule 1 and to
induce the secretion of IL-1 beta, IL-6, IL-8, and
MCP-1