◀ Back to MYLIP
MYLIP — ZFP36
Text-mined interactions from Literome
Gebeshuber et al., EMBO Rep 2009
(Breast Neoplasms...) :
Overexpression of
miR-29a suppressed the expression of
tristetraprolin (TTP) , a protein involved in the degradation of messenger RNAs with AU-rich 3'-untranslated regions, and led to EMT and metastasis in cooperation with oncogenic Ras signalling
Dugas et al., Neuron 2010
:
miR-219 directly
represses the expression of PDGFRalpha, Sox6, FoxJ3, and
ZFP238 proteins, all of which normally help to promote OPC proliferation
Semaan et al., PloS one 2011
(Arthritis, Rheumatoid) :
Conversely, transfection of
miR-346 in LPS activated THP-1 cells
increased TTP mRNA expression and inhibited TNF-a release
Hemida et al., Cell Mol Life Sci 2013
(Coxsackievirus Infections...) :
Finally, analyses of the signalling cascade downstream of ZFP-148 revealed that
miR-203 induced suppression of
ZFP-148 differentially regulated the expression of prosurvival and proapoptotic genes of the Bcl-2 family proteins as well as the cell cycle regulators
Al-Ahmadi et al., J Pathol 2013
(Breast Neoplasms...) :
MiR-29a recognized a seed target in the TTP 3 ' UTR and a cell-permeable
miR-29a inhibitor
increased TTP activity towards HuR 3 ' UTR
Bhattacharyya et al., Biochem Biophys Res Commun 2013
(Cystic Fibrosis...) :
While KSRP promotes enhanced processing of miR-155 precursors to mature miR-155, over-expression of
TTP in the CF lung epithelial cells
suppresses expression of
miR-155 ... We find that
TTP induces the expression of
miR-1 , which appears to be a regulator of miR-155 biogenesis in CF lung epithelial cells