Gene interactions and pathways from curated databases and text-mining

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MYLIP — ZFP36

Text-mined interactions from Literome

Gebeshuber et al., EMBO Rep 2009 (Breast Neoplasms...) : Overexpression of miR-29a suppressed the expression of tristetraprolin (TTP) , a protein involved in the degradation of messenger RNAs with AU-rich 3'-untranslated regions, and led to EMT and metastasis in cooperation with oncogenic Ras signalling
Dugas et al., Neuron 2010 : miR-219 directly represses the expression of PDGFRalpha, Sox6, FoxJ3, and ZFP238 proteins, all of which normally help to promote OPC proliferation
Semaan et al., PloS one 2011 (Arthritis, Rheumatoid) : Conversely, transfection of miR-346 in LPS activated THP-1 cells increased TTP mRNA expression and inhibited TNF-a release
Hemida et al., Cell Mol Life Sci 2013 (Coxsackievirus Infections...) : Finally, analyses of the signalling cascade downstream of ZFP-148 revealed that miR-203 induced suppression of ZFP-148 differentially regulated the expression of prosurvival and proapoptotic genes of the Bcl-2 family proteins as well as the cell cycle regulators
Al-Ahmadi et al., J Pathol 2013 (Breast Neoplasms...) : MiR-29a recognized a seed target in the TTP 3 ' UTR and a cell-permeable miR-29a inhibitor increased TTP activity towards HuR 3 ' UTR
Bhattacharyya et al., Biochem Biophys Res Commun 2013 (Cystic Fibrosis...) : While KSRP promotes enhanced processing of miR-155 precursors to mature miR-155, over-expression of TTP in the CF lung epithelial cells suppresses expression of miR-155 ... We find that TTP induces the expression of miR-1 , which appears to be a regulator of miR-155 biogenesis in CF lung epithelial cells