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BCR — HRAS

Text-mined interactions from Literome

Tamir et al., Immunity 2000 : This function is reportedly mediated in part by inhibition of B cell antigen receptor (BCR) mediated p21ras activation, though the basis of this inhibition is unknown
Ehrhardt et al., Mol Cell Biol 2004 : In contrast, ligation of the BCR or TCR resulted in activation of H-Ras , N-Ras, and K-Ras 4B, but not M-Ras
Harrison-Findik et al., Oncogene 1995 (Leukemia, Myelogenous, Chronic, BCR-ABL Positive) : P210 BCR/abl tyrosine kinase induces tyrosine phosphorylation of Shc, and activation of p21ras and PI 3-Kinase
Pao et al., J Immunol 1997 (Plasmacytoma) : Expression of the phosphotyrosine phosphatase CD45 is essential for B cell Ag receptor (BCR) mediated p21ras activation and calcium mobilization
Skorski et al., EMBO J 1997 (Cell Transformation, Neoplastic...) : SH2 domain BCR/ABL mutants deficient in PI-3k activation failed to stimulate Akt kinase, a recently identified PI-3k downstream effector with oncogenic potential, but did activate p21 RAS and p70 S6 kinase