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BID — FAS
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Belka et al., Oncogene 2000
:
We provide evidence that both, radiation and
CD95 stimulation,
induce the rapid activation of caspase-8 and
BID followed by apoptosis in Jurkat T-cells
Wei et al., Genes Dev 2000
:
TNFR1/Fas engagement
results in the cleavage of cytosolic
BID to truncated tBID, which translocates to mitochondria
Wang et al., J Biol Chem 2003
:
In human KB epithelial cells expressing the caspase-resistant mutant crBAP31,
Fas stimulation
resulted in cleavage of
BID and insertion of BAX into mitochondrial membrane, but subsequent oligomerization of BAX and BAK, egress of cytochrome c to the cytosol, and apoptosis were impaired
Schug et al., Cell Death Differ 2011
:
In this study, we have identified a native complex containing caspase-8 and BID on the mitochondrial membrane, and showed that death receptor activation by
Fas or tumor necrosis factor related apoptosis inducing ligand ( TRAIL )
induced the cleavage of
BID ( tBID formation ) within this complex