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ANXA1 — IL10
Text-mined interactions from Literome
Ferlazzo et al., Int Immunopharmacol 2003
:
In macrophage ( J774 ) cell line cultures primed with lipolysaccharide (LPS), recombinant
ANX-1 stimulated
IL-10 release in a dose- and time dependent manner ... In addition,
ANX-1 stimulated
IL-10 release may also be responsible for the inhibition of IL-12 mRNA expression and, consequently, IL-12 synthesis
Parente et al., Inflamm Res 2004
:
The inhibition of iNOS expression may be caused by the stimulation of
IL-10 release
induced by
ANXA1 in macrophages
Schuetze et al., Int Immunol 2005
:
Whereas p19 was induced early and transiently, p40 and
p35 were up-regulated later and then continuously, but the secretion of IL-23 and IL-12p70 was significantly
reduced by
IL-10
Souza et al., J Immunol 2007
(Inflammation...) :
The required
role of endogenously produced lipoxin A4 and
annexin-1 for the production of
IL-10 and inflammatory hyporesponsiveness in mice