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GPI — IL10
Text-mined interactions from Literome
Shimizu et al., Int J Antimicrob Agents 1999
(Mycobacterium avium-intracellulare Infection) :
Yokuinin reduced
IL-10 production by M. avium infected macrophages ph. ( M phis ) but did not
affect M
phi TFG-beta production
Sano et al., Kekkaku 1999
:
Half sized SLPI did not affect IL-10 production of LPS stimulated M phi s, while it caused slight
enhancement of
IL-10 production by MAC infected M
phi s. M phi TGF-beta production was initiated in the middle phase ( day 7 ) of M phi cultivation and continued until day 14
Kahlke et al., Cytokine 2000
(Hemorrhage...) :
In contrast, IL-1beta and IL-6 production by Mbeta from young males was suppressed and IL-10 production enhanced following trauma-haemorrhage, whereas Mstraight
phi from aged males produced elevated levels of IL-1beta and IL-6 and
suppressed levels of
IL-10 following trauma-haemorrhage
Gratchev et al., Skin Pharmacol Appl Skin Physiol 2001
(Skin Diseases) :
Among polarized APC, effector macrophages are classically activated by mediators such as IFN-gamma, TNF-alpha or LPS ( M phi 1 ), while M
phi 2 are alternatively
activated by IL-4,
IL-10 or PGE ( 2 )
Bogdan et al., J Exp Med 1991
:
At 10 U/ml,
IL-10 markedly
suppressed m
phi release of reactive oxygen intermediates ( ROI ) ( IC50 3.7 +/- 1.8 U/ml ), but only weakly inhibited m phi release of reactive nitrogen intermediates ( RNI )
Conroy et al., PloS one 2009
(Inflammation...) :
Plasmodium falciparum
GPI ( pfGPI ) enhanced C5a receptor expression ( CD88 ) on monocytes, and the co-incubation of monocytes with C5a and pfGPI
resulted in the synergistic induction of cytokines ( IL-6, TNF, IL-1beta, and
IL-10 ), chemokines ( IL-8, MCP-1, MIP1alpha, MIP1beta ) and the anti-angiogenic factor sFlt-1 in a time and dose dependent manner
Alleva et al., Immunobiology 1995
(Neoplasm Invasiveness) :
IL-10 strongly reduced or
inhibited M
phi production of these molecules
Mandrekar et al., Cytokine 1996
(Alcoholic Intoxication) :
Finally, our data demonstrate that ethanol induced elevated M phi
IL-10 contributes to the decreased M
phi TNF-alpha production seen after acute ethanol treatment ... However, observation of an ethanol induced decrease in TNF-alpha mRNA as early as 1.5 h after stimulation indicate that ethanol has an additional,
IL-10 independent,
effect on M
phi TNF-alpha production
Sasaki et al., Blood 1997
(Hematologic Neoplasms...) :
Phorbol 12-myristate 13-acetate ( PMA ),
interleukin-1 (IL-1), IL-3, IL-6, granulocyte-macrophage colony stimulating factor ( GM-CSF ), thrombopoietin (TPO), and tumor necrosis factor-alpha (TNF-alpha)
enhanced PGI2-R mRNA expression