Dawes et al., Am J Vet Res 2008
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Effects of lactoferrin on LPS induced gene expression of cyclooxygenase (COX)-2 and matrix metalloproteinase (MMP)-9 were monitored by use of PCR assays
Naot et al., Bone 2011
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Our study has provided the first evidence that COX2 and NFATc1 activities are increased by lactoferrin , and demonstrated a role for each of these molecules as mediators of the mitogenic effects of lactoferrin in osteoblasts