López et al., Int J Cardiol 2012
(Aortic Valve Stenosis...) :
Strikingly, when TLRs sensing viral patterns were studied, a sustained TLR3 mediated activation of NF-?B, a ?B-independent induction of catalytically active cyclooxigenase (COX)-2 and ICAM-1 expression, and induction of expression of several chemokines were observed
Li et al., Glia 2011
:
TLR3 activation induced early expression of cyclooxygenase 2 (COX2) and delayed expression of membranous PGE synthase and secretion of PGE ( 2 ) ... Nonselective and COX2-selective inhibitors blocked TLR3 induction of TNFa and IL-6