Gene interactions and pathways from curated databases and text-mining

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CXCL1 — NFKBIA

Text-mined interactions from Literome

Devalaraja et al., Cancer Res 1999 (Melanoma) : Elevated constitutive IkappaB kinase activity and IkappaB-alpha phosphorylation in Hs294T melanoma cells lead to increased basal MGSA/GRO-alpha transcription
Edwards et al., Mol Immunol 2007 : Focusing on CXCL8, both rhinovirus infection and dsRNA treatment required IkappaB kinase-beta for induction of CXCL8
Bachmeier et al., Carcinogenesis 2008 (Breast Neoplasms) : Using small interfering RNA techniques, we elucidated the underlying molecular mechanism revealing that reduction of CXCL1 and -2 messenger RNA levels is NFkappaB dependent and requires intact IkappaBalpha expression