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AHSA1 — BAX

Text-mined interactions from Literome

Gomez-Lazaro et al., Mol Pharmacol 2007 : Our data suggest that malonate induced ROS production and subsequent p38 MAP kinase activation mediates the activation of the pro-apoptotic Bax protein to induce mitochondrial membrane permeabilization and neuronal apoptosis
Karunakaran et al., J Neurosci 2008 (Disease Models, Animal...) : p38 activation results in downstream phosphorylation of p53 and increased p53 mediated transcription of Bax and Puma in the ventral midbrain
Haag et al., Exp Hematol 2009 (Leukemia, Myeloid, Acute) : Notably, GO treatment also caused proapoptotic conformation of Bak and Bax and activation of stress activated protein kinase p38 in responsive but not in resistant AML cells
Owens et al., Cell Death Differ 2009 : The inhibition of p38MAPK did not prevent Bax translocation, but its activity was required for mitochondrial Bax to bring about MOMP
Wakeman et al., Am J Physiol Gastrointest Liver Physiol 2012 (Short Bowel Syndrome) : p38 regulated Bax activation appears to be an important mechanism underlying resection induced apoptosis