Gene interactions and pathways from curated databases and text-mining

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IL8 — PDLIM7

Text-mined interactions from Literome

Eliopoulos et al., J Biol Chem 1999 : In addition, we have found that p38 inhibition significantly impaired LMP1 mediated interleukin-6 and -8 expression
Dawson et al., Virology 2000 (Nasopharyngeal Neoplasms) : Although B95.8-LMP1 induced growth inhibition, expression of certain cell surface molecules ( CD40, CD44, and CD54 ), and secretion of interleukin-6 and -8 in SCC12F cells, stable CAO-LMP1 expression failed to elicit these effects
Yoshizaki et al., Clin Cancer Res 2001 (Epstein-Barr Virus Infections...) : The expression of LMP-1 transactivated IL-8 promoter, as demonstrated by IL-8 promoter luciferase reporter assay ... These results suggested that LMP-1 induces expression of IL-8 through the nuclear factor kappaB binding site, which may contribute in part to angiogenesis in NPC
Yoshizaki et al., Histol Histopathol 2002 (Carcinoma...) : LMP-1 also induces vascular endothelial growth factor through cyclooxygenase-2 activation and interleukin-8 through NF-kappaB activation
Ren et al., Laryngoscope 2004 (Carcinoma...) : LMP1 transactivated the IL-8 promoter, whereas EBERs did not ... LMP1 induces IL-8 mainly through the activation of NF-kappa B and partly through AP-1 in NPC model cell lines, NPC-KT, and this suggests that LMP1 plays an important role in the angiogenesis of NPC