Zou et al., Cell Signal 2006
(Hypertrophy...) :
We also examined hypertrophy associated MAP kinase pathways, and RGS2 overexpression completely prevented the activation of ERK by PE
Semplicini et al., J Hypertens 2006
(Hypertension) :
Reduced expression of regulator of G-protein signaling 2 ( RGS2 ) in hypertensive patients increases calcium mobilization and ERK1/2 phosphorylation induced by angiotensin II
Anger et al., J Biochem Mol Biol 2007
:
RGS2 had no effect on M ( 2 ) /G ( i/o ) -induced ERK activation
Calò et al., J Hypertens 2008
(Bartter Syndrome...) :
Silencing RGS-2 in BS/GS patients increased Ang II-induced Cai2+ release and ERK 1/2 phosphorylation in silenced cells compared with not silenced cells [ 59.3 +/- 10.8 ( peak-basal ) vs. 40.5 +/- 14.1 nmol/l, P = 0.017 and 0.84 +/- 0.06 vs. 0.64 +/- 0.08 nmol/l, P < 0.03, respectively ], whereas they were not different compared with controls ( 60.1 +/- 4.3 and 0.91 +/- 0.03 nmol/l )