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BMP15 — PTH

Text-mined interactions from Literome

Nakao et al., Bone 2009 : Parathyroid hormone enhances bone morphogenetic protein activity by increasing intracellular 3 ', 5'-cyclic adenosine monophosphate accumulation in osteoblastic MC3T3-E1 cells ... H89 ( PKA inhibitor ) almost completely abolished PTH actions on BMP signaling ... These results suggest that PTH enhances BMP signaling when PTH induced intracellular cAMP level is maintained for a few hours, accelerating BMP actions to promote osteoblastic function and anabolic actions of new bone formation
Yang et al., Ann N Y Acad Sci 2010 (Bone Diseases, Developmental) : This study provides an in vivo tool to study the role of BMPRII in BMP/Smad signaling and the regulation of this pathway by PTH and Wnts