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CXCL10 — IL4

Text-mined interactions from Literome

Albanesi et al., J Immunol 2000 (Calcium Signaling...) : IL-4 , but not IL-10 or IL-17, significantly up-regulated IFN-gamma- or TNF-alpha induced IP-10, Mig, and I-TAC mRNA accumulation in keratinocytes and increased the levels of IP-10 and Mig in keratinocyte supernatants
Giustizieri et al., J Allergy Clin Immunol 2001 (Dermatitis, Atopic...) : IL-4 weakly induced IP-10 , RANTES, and IL-8 but not MCP-1
Kanda et al., Clin Exp Allergy 2002 (Dermatitis, Atopic...) : MF induced IL-4 and macrophage derived chemokine (MDC) secretion in AD patients, while induced IFN-gamma and interferon-inducible protein of 10 kDa (IP-10) secretion in PV patients, however, did not induce either secretion in normal subjects
Kakinuma et al., Cytokine 2002 : Furthermore, the effects of IL-4 on TARC and IP-10 production in these cells were detected in a dose dependent manner
Wright et al., J Clin Immunol 2003 (Osteomyelitis...) : We investigated the potential down-regulators of chemokine secretion IL-4 , IL-10, IL-13, dexamethasone, and PGE2, IL-10 and IL-13 down-regulate M. tuberculosis induced IL-8, IP-10 , RANTES, and MCP-1 secretion from MG-63 cells by between 48 and 94 % ( P < 0.05 ) but do not inhibit chemokine gene transcription
Thomas et al., J Immunol 2004 (Bronchial Hyperreactivity) : In lymphocytes restimulated with CXCL9 and allergen in vitro, CXCL9 down-regulated IL-4 expression and up-regulated IFN-gamma expression, suggesting that CXCL9 is able to direct activated lymphocytes toward a Th1-type phenotype
Wright et al., Microbes Infect 2004 : IL-10 and IL-13 reduced S. aureus induced osteoblast C-X-C chemokine secretion, whereas IL-4 decreased CXCL8 secretion 2.5-fold and increased CXCL10 secretion 3-fold ( all P < 0.05 )
Herder et al., Int J Obes Relat Metab Disord 2007 : In cultures of human mature adipocytes and in vitro differentiated adipocytes, IP-10 expression under basal conditions and in the presence of IFNgamma, lipopolysaccharide (LPS) or interleukin (IL)-4 was characterized by reverse transcriptase-polymerase chain reaction, Luminex technology and immunofluorescence ... In in vitro differentiated adipocytes from s.c. and mammary depots and in mature s.c. adipocytes, IP-10 secretion was strongly upregulated by IFNgamma, whereas LPS or IL-4 did not affect IP-10 expression in s.c. mature adipocytes
Méndez-Samperio et al., Mediators Inflamm 2006 : We found that, although M. bovis BCG induced gene expression of CXCL-8 and CXCL-10 in M. bovis BCG infected human epithelial cells, CXCL-8 mRNA level was significantly reduced by IL-4 , whereas no significant effect of IL-4 was observed on CXCL10 mRNA level ... Furthermore, we found a similar effect of IL-4 on M. bovis BCG induced CXCL-8 and CXCL-10 secretion by using other human epithelial A549 cell line
Huang et al., Am J Physiol Lung Cell Mol Physiol 2007 : IL-4 stimulates the expression of CXCL-8 , E-selectin, VEGF, and inducible nitric oxide synthase mRNA by equine pulmonary artery endothelial cells
Hosokawa et al., J Periodontal Res 2009 (Periodontitis) : However, interleukin-4 and interleukin-13 inhibited CXCL10 production by interferon-gamma stimulated or tumor necrosis factor-alpha-stimulated-human gingival fibroblasts ... However, interleukin-4 and interleukin-13 inhibited CXCL10 production by interferon-gamma stimulated or tumor necrosis factor-alpha-stimulated-human gingival fibroblasts ... On the other hand, interleukin-17A and interleukin-22 enhanced CXCL10 production by human gingival fibroblasts treated with interferon-gamma and inhibited CXCL10 production by tumor necrosis factor-alpha stimulated human gingival fibroblasts
Tousi et al., Neurosci Lett 2012 (Parkinson Disease) : a-Synuclein potentiates interleukin-1ß induced CXCL10 expression in human A172 astrocytoma cells
Deng et al., J Immunol 1994 : Mechanisms of IL-4 mediated suppression of IP-10 gene expression in murine macrophages ... The mechanisms involved in negative regulation of IFN-gamma induced IP-10 mRNA expression by IL-4 have been examined in an immortalized murine macrophage cell line ( ANA-1 ) ... Together, these findings demonstrate that IL-4 inhibits IP-10 mRNA production in murine macrophages by suppressing the formation of new transcripts
Gangur et al., FASEB J 1998 : We examined the effect of recombinant human IP-10 ( rhIP-10 ) on human interferon gamma (IFN-gamma) and interleukin 4 (IL-4) production by fresh peripheral blood mononuclear cells