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IL4 — SETBP1
Text-mined interactions from Literome
Jahreis et al., Br J Dermatol 2000
(Dermatitis, Atopic) :
Both antigens, as well as
SEB ,
induced IL-4 and IFN-gamma secretion in patients and controls
Smart et al., Clin Exp Allergy 2002
(Hypersensitivity) :
Symptomatic atopic children had reduced
SEB induced IFN-gamma and increased SEB induced
IL-4 and IL-5 as compared with non-atopic controls ... In contrast,
SEB induced IFN-gamma,
IL-4 and IL-5 production in asymptomatic atopics was not significantly different from the non-atopic control subjects
Hisano et al., Arch Dermatol Res 2003
(Dermatitis, Atopic) :
Polyphenon inhibited the lethal toxicity of SEB and the
SEB induced production of TNF-alpha, IFN-gamma and
IL-4 following its intraperitoneal administration to BALB/c mice
Matsui et al., J Interferon Cytokine Res 2004
(Dermatitis, Atopic) :
MDM inhibited
SEB induced mRNA expression of the Th2 cytokines
interleukin-4 (IL-4) and IL-5 in PBMCs from patients with AD
Lin et al., Allergy 2007
(Dermatitis, Atopic) :
Using immunofluorescence staining followed by flow cytometric analysis and real-time PCR, we analyzed peripheral blood mononuclear cells with or without
staphylococcal enterotoxin B (SEB) stimulation in the
presence or absence of recombinant
IL-4 or anti-IL-4 neutralizing antibodies in 16 AD patients and 14 healthy subjects
Ardern-Jones et al., Proc Natl Acad Sci U S A 2007
(Dermatitis, Atopic) :
This response was mediated by two synergistic mechanisms : first, SEB induced IFN-gamma promoted class II and intercellular adhesion molecule-1 expression by presenting keratinocytes ; and second,
SEB induced
IL-4 directly amplified allergen-specific CD4 ( + ) T cell production of many cytokines
Hayworth et al., Clin Exp Immunol 2009
(Staphylococcal Infections) :
Here, we report that bovine LF ( bLF ) was indeed able to attenuate
SEB induced proliferation,
interleukin-2 production and CD25 expression by human leucocyte antigen ( HLA ) -DR4 transgenic mouse T cells
Sperber et al., Clin Diagn Lab Immunol 1995
:
In IEL, SEE
induced no IL-2,
IL-4 , or gamma interferon but produced IL-6 and TNF, while
SEB stimulation resulted in no IL-2 or gamma interferon but did result in detectable IL-4, IL-6, and TNF
Nakata et al., J Immunol 1995
:
When rhIL-1 was administered within 24 h after SEB inoculation, the cytokine interfered with tolerance induction ; V beta 8+CD4 T cells from mice that had been treated with both SEB and IL-1 proliferated in
response to
SEB and produced IL-2,
IL-4 , and IFN-gamma upon TCR/CD28 cross linking
Cardell et al., Eur J Immunol 1993
:
High frequencies of cells producing interleukin-2 (IL-2) and interferon-gamma (IFN-gamma) were induced, but very low frequencies of CD4+ T cells produced
IL-4 , IL-5 or IL-10 in
response to
SEB ... We further demonstrate that
IL-4 and IL-10 or IFN-gamma production was selectively
induced in resting, high-density CD4+ T cells during primary stimulation, by
SEB + IL-4 or SEB
König et al., Int Arch Allergy Immunol 1995
(Dermatitis, Atopic) :
In contrast to normal donors T cells from donors with AD predominantly express mRNA for
IL-4 , IL-5, and only diminished levels for IFN-gamma and IL-12 upon
stimulation with
SEB and SEA
Höidén et al., Scand J Immunol 1993
:
The cells that had been induced to produce mainly IFN gamma during the primary
SEB stimulation, or during
stimulation with
IL4 and IL10, synthesized the same lymphokines at restimulation, regardless of stimuli and were unaffected by exogenous IL4
Hartung et al., J Infect Dis 1998
(Disease Progression...) :
Patients with advanced HIV infection showed reduced IL-2 and
IL-4 release in the
presence of
SEB