Gene interactions and pathways from curated databases and text-mining

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IL4 — SETBP1

Text-mined interactions from Literome

Jahreis et al., Br J Dermatol 2000 (Dermatitis, Atopic) : Both antigens, as well as SEB , induced IL-4 and IFN-gamma secretion in patients and controls
Smart et al., Clin Exp Allergy 2002 (Hypersensitivity) : Symptomatic atopic children had reduced SEB induced IFN-gamma and increased SEB induced IL-4 and IL-5 as compared with non-atopic controls ... In contrast, SEB induced IFN-gamma, IL-4 and IL-5 production in asymptomatic atopics was not significantly different from the non-atopic control subjects
Hisano et al., Arch Dermatol Res 2003 (Dermatitis, Atopic) : Polyphenon inhibited the lethal toxicity of SEB and the SEB induced production of TNF-alpha, IFN-gamma and IL-4 following its intraperitoneal administration to BALB/c mice
Matsui et al., J Interferon Cytokine Res 2004 (Dermatitis, Atopic) : MDM inhibited SEB induced mRNA expression of the Th2 cytokines interleukin-4 (IL-4) and IL-5 in PBMCs from patients with AD
Lin et al., Allergy 2007 (Dermatitis, Atopic) : Using immunofluorescence staining followed by flow cytometric analysis and real-time PCR, we analyzed peripheral blood mononuclear cells with or without staphylococcal enterotoxin B (SEB) stimulation in the presence or absence of recombinant IL-4 or anti-IL-4 neutralizing antibodies in 16 AD patients and 14 healthy subjects
Ardern-Jones et al., Proc Natl Acad Sci U S A 2007 (Dermatitis, Atopic) : This response was mediated by two synergistic mechanisms : first, SEB induced IFN-gamma promoted class II and intercellular adhesion molecule-1 expression by presenting keratinocytes ; and second, SEB induced IL-4 directly amplified allergen-specific CD4 ( + ) T cell production of many cytokines
Hayworth et al., Clin Exp Immunol 2009 (Staphylococcal Infections) : Here, we report that bovine LF ( bLF ) was indeed able to attenuate SEB induced proliferation, interleukin-2 production and CD25 expression by human leucocyte antigen ( HLA ) -DR4 transgenic mouse T cells
Sperber et al., Clin Diagn Lab Immunol 1995 : In IEL, SEE induced no IL-2, IL-4 , or gamma interferon but produced IL-6 and TNF, while SEB stimulation resulted in no IL-2 or gamma interferon but did result in detectable IL-4, IL-6, and TNF
Nakata et al., J Immunol 1995 : When rhIL-1 was administered within 24 h after SEB inoculation, the cytokine interfered with tolerance induction ; V beta 8+CD4 T cells from mice that had been treated with both SEB and IL-1 proliferated in response to SEB and produced IL-2, IL-4 , and IFN-gamma upon TCR/CD28 cross linking
Cardell et al., Eur J Immunol 1993 : High frequencies of cells producing interleukin-2 (IL-2) and interferon-gamma (IFN-gamma) were induced, but very low frequencies of CD4+ T cells produced IL-4 , IL-5 or IL-10 in response to SEB ... We further demonstrate that IL-4 and IL-10 or IFN-gamma production was selectively induced in resting, high-density CD4+ T cells during primary stimulation, by SEB + IL-4 or SEB
König et al., Int Arch Allergy Immunol 1995 (Dermatitis, Atopic) : In contrast to normal donors T cells from donors with AD predominantly express mRNA for IL-4 , IL-5, and only diminished levels for IFN-gamma and IL-12 upon stimulation with SEB and SEA
Höidén et al., Scand J Immunol 1993 : The cells that had been induced to produce mainly IFN gamma during the primary SEB stimulation, or during stimulation with IL4 and IL10, synthesized the same lymphokines at restimulation, regardless of stimuli and were unaffected by exogenous IL4
Hartung et al., J Infect Dis 1998 (Disease Progression...) : Patients with advanced HIV infection showed reduced IL-2 and IL-4 release in the presence of SEB