Gene interactions and pathways from curated databases and text-mining

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EGF — PGR

Text-mined interactions from Literome

Sumida et al., Mol Cell Endocrinol 1990 : The role of growth factor signal transducers in the induction of the progesterone receptor by epidermal growth factor (EGF) and the potential sites of EGF antagonism by an antiestrogen were studied in fetal uterine cells in culture
Sumida et al., Pathol Biol (Paris) 1989 : Epidermal growth factor (EGF) stimulates both cell proliferation and the progesterone receptor 4-Hydroxytamoxifen, a tamoxifen metabolite and potent anti-oestrogen, completely inhibits the stimulatory effect of EGF on the progesterone receptor but has no effect on the EGF induced cell growth
Sumida et al., Endocrinology 1989 : Antiestrogens antagonize the stimulatory effect of epidermal growth factor on the induction of progesterone receptor in fetal uterine cells in culture
Sumida et al., Endocrinology 1988 : Insulin alone had no effect on progesterone receptor concentrations, but epidermal growth factor stimulated the progesterone receptor about as much as estradiol
Rao et al., Biochem Biophys Res Commun 1987 (Breast Neoplasms) : Progesterone receptor phosphorylation on serine residues was increased by 2-fold in cells treated with 10 nM progesterone ; EGF had no effect on progesterone mediated progesterone receptor phosphorylation