Gene interactions and pathways from curated databases and text-mining

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CCR7 — IRF6

Text-mined interactions from Literome

Giordano et al., J Immunol 2003 : Treatment during DC differentiation with either cAMP or cGMP analogues hampered LPS induced expression of CD83, DC-LAMP, and CCR7 and the ability of DCs to migrate toward CCL19/macrophage-inflammatory protein 3beta
Vizzardelli et al., Eur J Immunol 2006 : Among the counteracting effects we have observed an inhibition of Dex on the LPS induced up-regulation of the chemokine receptor CCR7
Amat et al., Br J Pharmacol 2006 (Arthritis) : Surprisingly, CCR1 knockout mice produced more TNFalpha than controls in response to LPS , and J-113863 decreased TNFalpha also in CCR1 null mice, indicating that its effect was unrelated to CCR1
Li et al., Blood 2007 (MAP Kinase Signaling System) : Specific inhibition of ERK during CB DC maturation enhanced LPS induced up-regulation of CCR7 and CXCR4 on CB DCs and their chemotaxis toward CCL19 and CXCL12, to a level similar to that of mature AB DCs ... Overall, monocyte derived CB DCs responded to LPS with stronger and sustained ERK activation, which negatively correlated with LPS induced up-regulation of CCR7 and CXCR4 on CB DCs and their migratory responses
Liu et al., Mol Immunol 2007 : Further studies show that the triptolide mediated inhibitory effects of LPS induced activation of phosphatidylinositol-3 kinase (PI3-K)/Akt and nuclear NF-kappaB activation are involved in down-regulation of COX-2 and CCR7 expression resulting in impaired migration to secondary lymphoid organs of DC
Jiang et al., J Immunol 2007 : NGF could markedly promote LPS induced expression of HLA-DR, CD40, CD80, CD83, CD86, CCR7 , secretion of IL-12p40 and proinflammatory cytokines IL-1, IL-6, TNF-alpha, and the T cell stimulating capacity of MoDCs, indicating that NGF can promote LPS induced DC maturation
Thomas et al., Clin Exp Immunol 2009 : Culture of primary ( native, non-monocyte derived ) human myeloid CD1c+CD11c+CD123 ( - ) DC ( mDC ) in the presence of Sb culture supernatant ( active component molecular weight < 3 kDa, as evaluated by membrane partition chromatography ) reduced significantly expression of the co-stimulatory molecules CD40 and CD80 ( P < 0.01 ) and the DC mobilization marker CC-chemokine receptor CCR7 ( CD197 ) ( P < 0.001 ) induced by the prototypical microbial antigen lipopolysaccharide (LPS)
van de Laar et al., J Immunol 2010 : Although dispensable for costimulatory molecule expression, the PI3K-PKB-mTOR signaling module was required for other important processes associated with DC function, including Ag uptake, LPS induced cytokine secretion, CCR7 expression, and T cell stimulation
Sica et al., J Exp Med 1997 : The present study was designed to investigate the effect of bacterial lipopolysaccharide (LPS) on C-C chemokine receptors ( CCR ) expressed in human mononuclear phagocytes
Minami et al., Toxicology 1998 : We investigated the penetration of cisplatin into the mouse cerebral cortex-rich region ( CCR ) induced by lipopolysaccharide (LPS) ... At doses of 500 mg/kg aminoguanidine, however, no effect was seen on the platinum level of the CCR induced by LPS