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IRF6 — SPP1

Text-mined interactions from Literome

Ka et al., Arthritis Res Ther 2007 (Disease Models, Animal...) : Monocyte chemoattractant protein-1 ( MCP-1 ) and osteopontin (OPN) expressions either in the baseline ( normal culture ) condition or in the presence of LPS were evaluated by real-time PCR, ELISA, or western blot analysis ... First, either in the baseline condition or in the presence of LPS , NZB/W MCs produced significantly higher levels of MCP-1 and OPN than the DBA/W MC controls
Kurokawa et al., Eur J Immunol 2009 (Bronchial Hyperreactivity) : Furthermore, significantly reduced levels of IL-12p70 expression were seen in LPS stimulated OPN ( -/- ) DC as compared with the WT DC, and the reduction was reversible by the addition of recombinant OPN ( rOPN )
Zhao et al., J Biol Chem 2010 : Mutation of the AP-1 site in OPN promoter completely ablates LPS induced OPN promoter activation ... Knockdown of c-Jun and c-Fos expression by small interfering RNA ( siRNA ) significantly decreases LPS induced OPN expression
Jin et al., Mol Cell Endocrinol 1990 : Besides IL-1 alpha, tumor necrosis factor alpha (TNF-alpha), lipopolysaccharides (LPS) and 1 alpha,25-dihydroxyvitamin D3 ( 1 alpha,25 ( OH ) 2D3 ) increased the osteopontin mRNA expression in both the clonal osteoblasts ( MC3T3-E1 ) and the primary osteoblast-like cells
Zhao et al., J Immunol 2011 : In the present study, we confirm that NF-?B also plays an important role in the setting of LPS stimulated OPN expression through binding to a distal regulatory element ... Furthermore, we demonstrate that p300 can form a complex with NF-?B and AP-1 and is involved in DNA looping and LPS induced OPN expression ... Therefore, we have identified an essential mechanism to remodel the local chromatin structures and spatial conformations to regulate LPS induced OPN expression
Lee et al., J Korean Med Sci 1998 : To investigate whether MCP-1, CINC, RANTES, osteopontin and ICAM-1 mRNA could be induced in cultured rat mesangial cells by interleukin-1beta(IL-1beta), tumor necrosis factor-alpha (TNF-alpha) and lipopolysaccharide (LPS) , and whether MCP-1 and CINC gene expression could be modulated by dexamethasone, Northern blot assays were performed ... On the other hand, IL-1beta, TNF-alpha and LPS had little effect on osteopontin gene expression but fetal calf serum could increase osteopontin mRNA