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FGF10 — INS

Text-mined interactions from Literome

Hiriart et al., Isr Med Assoc J 2001 : Moreover, both NGF and FGF enhance glucose induced insulin secretion
Wente et al., Diabetes 2006 (Diabetes Mellitus, Type 2...) : In islets isolated from diabetic rodents, FGF-21 treatment increased islet insulin content and glucose induced insulin secretion
Kharitonenkov et al., Endocrinology 2007 (Body Weight...) : When administered daily for 6 wk to diabetic rhesus monkeys, FGF-21 caused a dramatic decline in fasting plasma glucose, fructosamine, triglycerides, insulin , and glucagon
Izumiya et al., FEBS Lett 2008 : In cultured skeletal muscle cells, FGF21 expression and secretion was regulated by insulin , Akt transduction and LY294002
Xu et al., Am J Physiol Endocrinol Metab 2009 (Insulin Resistance...) : In ob/ob mice, FGF21 led to a 40-60 % decrease in blood glucose, insulin , and amylin levels within 1 h after injection, and the maximal effects were sustained for more than 6 h despite the 1- to 2-h half-life of FGF21 ... In DIO mice, FGF21 reduced fasting blood glucose and insulin levels and improved glucose tolerance and insulin sensitivity within 3 h of treatment
Vidaltamayo et al., Endocrine 1996 : We studied the effects of nerve growth factor (NGF), fibroblast growth factor ( FGF ) , and dibutyryl-cAMP ( dbcAMP ) on rat pancreatic ß-cell morphology and of NGF and dbcAMP on insulin secretion
Hamilton et al., J Cell Physiol 1985 : Their induction is, however, correlated with the ability of the polypeptide growth factor to stimulate DNA synthesis ; EGF, FGF , and serum induce the SIPs, whereas insulin does not, and insulin alone weakly stimulates DNA synthesis in these cells
Sadovnikova et al., Biull Eksp Biol Med 1988 : The effects of fibroblast growth factor ( FGF ) and nerve growth factor (NGF) on DNA synthesis and insulin secretion were studied in 4-5-day cultures of the isolated neonatal rat islets
Takeyama et al., FEBS Lett 1985 (Colonic Neoplasms) : In Swiss 3T3 cells, colon tumor promoting deoxycholate ( DOC ) enhanced DNA synthesis which was induced by fibroblast growth factor ( FGF ) in the presence of insulin ... In contrast to these bile acids, 12-O-tetradecanoylphorbol-13-acetate ( TPA ) induced DNA synthesis fully without FGF in the presence of insulin ... In these cells, FGF still induced DNA synthesis in the presence of insulin , but the maximal level was reduced to about one third of that in the control cells
Imamura et al., Hepatology 1996 : In the presence of serum and physiological concentration of insulin , FGF-C ( 1211 ) by itself induces as much as 55 % of hepatocytes in culture to proliferate and up to 88 % when used in combination with hepatocyte growth factor or epidermal growth factor