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CNP — TNF

Text-mined interactions from Literome

Jana et al., Free Radic Biol Med 2005 (Encephalomyelitis, Autoimmune, Experimental...) : Interestingly, both IL-1beta and TNF-alpha markedly inhibited the expression of MOG, CNPase , and PLP but not MBP, the effect that was blocked by antioxidants such as N-acetylcysteine (NAC) and pyrrolidine dithiocarbamate ( PDTC )
Jerczynska et al., Regul Pept 2009 : We have previously shown that CNP inhibits both basal and TNFalpha induced expression of PAI-1 in human endothelial cells
Osterbur et al., Res Vet Sci 2013 : These data indicate that lipopolysaccharide, TNF-a and IL-1ß regulate CNP production from canine vascular endothelium and of the stimulants tested, IL-1ß is the predominant inducing factor
Suga et al., Endocrinology 1993 : While interleukin (IL)-2 had no significant effect on CNP secretion, IL-1 alpha, IL-1 beta and tumor necrosis factor (TNF)-alpha stimulated CNP secretion in a time- and dose dependent manner
Suga et al., Endocrinology 1998 : These results indicate that endothelial production of CNP is stimulated mainly by TNF alpha released from THP-1 derived macrophages in the coculture