Gene interactions and pathways from curated databases and text-mining

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COL1A1 — CTGF

Text-mined interactions from Literome

Weinbaum et al., Macromol Biosci 2010 : MBD-CTGF , but not CTGF alone, led to a two-fold enhancement of COL1A1 expression
Saito et al., Arch Dermatol Res 2012 (Keloid) : TGF-ß1 stimulated mRNA expression of TGFB1, CTGF, aSMA, and Col1A1 in keloid fibroblasts, while pirfenidone significantly inhibited mRNA expression of CTGF and aSMA in the identical cells
Zhu et al., International journal of ophthalmology 2013 : Preincubation of ARPE-19 with Y27632 ( 10mmol/L ) significantly prevented CTGF or TGF- ß induced fibronectin ( P=0.005, P=0.003 respectively ), MMP-2 ( P= 0.003, P=0.002 ), COL1A1 ( P=0.006, P=0.003 ), and COL1A2 ( P=0.006, P=0.004 ) gene expression, but not laminin ( P=0.375, P=0.516 )
Frazier et al., J Invest Dermatol 1996 : In NRK fibroblasts, both TGF-beta and CTGF significantly increased the transcripts encoding alpha 1 type I collagen , alpha 5 integrin, and fibronectin