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COL1A1 — CTGF
Text-mined interactions from Literome
Weinbaum et al., Macromol Biosci 2010
:
MBD-CTGF , but not CTGF alone,
led to a two-fold enhancement of
COL1A1 expression
Saito et al., Arch Dermatol Res 2012
(Keloid) :
TGF-ß1 stimulated mRNA expression of TGFB1, CTGF, aSMA, and
Col1A1 in keloid fibroblasts, while pirfenidone significantly
inhibited mRNA expression of
CTGF and aSMA in the identical cells
Zhu et al., International journal of ophthalmology 2013
:
Preincubation of ARPE-19 with Y27632 ( 10mmol/L ) significantly prevented
CTGF or TGF- ß
induced fibronectin ( P=0.005, P=0.003 respectively ), MMP-2 ( P= 0.003, P=0.002 ),
COL1A1 ( P=0.006, P=0.003 ), and COL1A2 ( P=0.006, P=0.004 ) gene expression, but not laminin ( P=0.375, P=0.516 )
Frazier et al., J Invest Dermatol 1996
:
In NRK fibroblasts, both TGF-beta and
CTGF significantly
increased the transcripts encoding
alpha 1 type I collagen , alpha 5 integrin, and fibronectin