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NGF — PRKAR1B

Text-mined interactions from Literome

Obara et al., J Cell Sci 2004 : In these cells, Rap1 is required for cAMP/PKA signaling to ERKs and also for the sustained activation of ERKs by NGF ... These results strongly indicate that PKA phosphorylation of Src at S17 is essential for cAMP and NGF signaling in PC12 cells and identify PKA as an important downstream target of NGF
Park et al., Mol Cells 2006 : The p38 mitogen activated protein kinase ( MAPK ) inhibitor, SB203580, phosphatidylinositol 3-kinase (PI-3K) inhibitor, LY294003, protein kinase A (PKA) inhibitor, H89, and protein kinase C ( PKC ) inhibitor, chelerythrine, had no effect on activation of promoter IV by NGF
Yao et al., J Biol Chem 1998 : The cyclic adenosine monophosphate dependent protein kinase (PKA) is required for the sustained activation of mitogen activated kinases and gene expression by nerve growth factor ... Here we show that maximal sustained activation of ERK1 by NGF requires PKA ... Inhibitors of PKA partially blocked activation of ERK1 by NGF but had no effect on activation of ERK1 by EGF