Wang et al., J Immunol 2000
(Multiple Sclerosis) :
We demonstrate that IFN-beta-1b significantly inhibits inducible IL-12 p40 up to 80 % and biologically active IL-12 p70 up to 70 % beginning at a dose of 10 IU/ml
Ito et al., Int Immunol 2005
:
In the presence of exogenously added IFN-beta , IL-12 p40 and IL-12 p70 production was inhibited after LSO stimulation, but IL-12 p70 production was enhanced after PGN stimulation
Carrieri et al., Immunopharmacol Immunotoxicol 2008
(Multiple Sclerosis, Relapsing-Remitting) :
We examined the effects of interferon (IFN)beta-1a on interleukin (IL)-12p70 and IL-10 secretion in 27 Relapsing Remitting Multiple Sclerosis ( RRMS ) patients, divided in responders and non-responders