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Text-mined interactions from Literome

Bonacchi et al., J Biol Chem 2001 : The increase in ERK activity was inhibited by genistein and PP1 , but not by wortmannin, indicating that Src activation is necessary for the activation of the Ras/ERK pathway by CXCR3
Gao et al., J Pharmacol Exp Ther 2001 : ERK activation induced by the PKC activator phorbol myristate acetate was inhibited by PTX, PP1 , AG1478, and calphostin C ... In contrast, activation of ERK by lysophosphatidic acid, a Gi-coupled receptor activator, was inhibited by PTX, PP1 , and AG1478, but not by calphostin C
Liu et al., J Leukoc Biol 2001 (Gout) : PP1 inhibited crystal induced phosphorylation of ERK1/2 and IkappaBalpha and suppressed IkappaB kinase (IKK) activation and NF-kappaB binding to the IL-8 promoter, signals that mediate MSU induced IL-8 expression
Kodama et al., J Mol Cell Cardiol 2002 (MAP Kinase Signaling System) : Furthermore, activation of ERK and Shc, and c- fos gene expression were significantly inhibited by AG1478 but not by cytochalasin D or PP1
Samarakoon et al., J Cell Sci 2002 (MAP Kinase Signaling System) : The restrictive ( src-family ) kinase inhibitor PP1 completely inhibited induced, as well as basal, ERK activity in a coupled immunoprecipitation myelin-basic-protein-phosphorylation assay and ablated shape initiated PAI-1 mRNA expression
Garcia et al., FEBS Lett 2002 : This suggests that either PP1 or PP2A or both are necessary for ERK5 activation
Mitsuhashi et al., J Biol Chem 2003 (MAP Kinase Signaling System) : First, we found that inhibition of PP1 in COS-7 cells by TC specifically suppresses activation of ERK , among three MAPK kinases ( ERK, JNK, and p38 )
Samarakoon et al., J Cell Physiol 2003 : ERK activation in response to microfilament disruption was inhibited completely by the broad-spectrum tyrosine kinase inhibitor genistein and the relatively src-kinase selective compound PP1
Yung et al., J Neurochem 2003 : The PP1/PP2A phosphatase inhibitors okadaic acid and caliculyn A, but not cyclosporine A, delayed the removal of ERK and Akt phosphorylation under OGD
Uchida et al., Exp Cell Res 2003 (Carcinoma, Squamous Cell...) : SDF-1alpha also activated Src family kinases (SFKs), and its inhibitor PP1 diminished the SDF-1alpha induced chemotaxis and activation of both ERK1/2 and Akt/PKB
Zhao et al., Mol Pharmacol 2006 : It is interesting that the nuclear accumulation of ERK1/2 and Elk phosphorylation was completely blocked by dominant negative Rho, Y27632, PP1 , and latrunculin B, indicating that the Rho/ROCK pathway, Src kinase, and the actin cytoskeleton were required in this process
Rodríguez et al., Cell Signal 2006 : Most important, IL-1 induced ERK1/ERK2 activation is inhibited by PP1 , a known inhibitor of Src tyrosine kinases, but this tyrosine kinase activity is not required for IL-1 to activate other MAP kinases such as p38 and JNK
Kang et al., Toxicological sciences : an official journal of the Society of Toxicology 2006 : Damnacanthal or PP1 substantially blocked the silica induced activation of ERK1/2
Thobe et al., Am J Physiol Cell Physiol 2006 (Anoxia...) : However, PP1 did not prevent the increase in KC ERK1/2 or JNK phosphorylation
Meng et al., Free Radic Biol Med 2007 : Src kinase inhibitor PP1 and Src siRNA blocked IGF-I induced activation of EGFR and ERK1/2