Gene interactions and pathways from curated databases and text-mining

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MAP2K7 — SMAD7

Text-mined interactions from Literome

Edlund et al., Mol Biol Cell 2003 (Prostatic Neoplasms) : Transforming growth factor-beta1 ( TGF-beta ) -induced apoptosis of prostate cancer cells involves Smad7 dependent activation of p38 by TGF-beta activated kinase 1 and mitogen activated protein kinase kinase 3
Chen et al., Exp Cell Res 2010 : Inhibition of mitogen activated protein kinase kinase 1 ( MEK 1 ) either directly with PD98059 or with MEK 1 siRNA resulted in inhibition of EPO mediated suppression of EMT and Smad signal transduction in TGF-beta1 treated cells