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AHR — EPHB2
Text-mined interactions from Literome
Chen et al., J Biol Chem 2005
:
ERK kinase inhibition
stabilizes the
aryl hydrocarbon receptor : implications for transcriptional activation and protein degradation
Cheon et al., Exp Mol Med 2007
(MAP Kinase Signaling System) :
PD153035, an EGFR inhibitor, as well as alpha-NF significantly reduced ERK phosphorylation, suggesting that
ERK activation by TCDD was
mediated by both EGFR and
AhR
Xie et al., Am J Physiol Gastrointest Liver Physiol 2012
(Colonic Neoplasms) :
With the use of two human colon cancer cell lines, H508 and SNU-C4, we examined the
effects of
AhR ligands including 2,3,7,8-tetrachlorodibenzo-p-dioxin ( TCDD ) on cell proliferation and activation of EGFR,
ERK1/2 , and Src kinases
Pontillo et al., Toxicol Appl Pharmacol 2013
(Mammary Neoplasms, Experimental...) :
We have found that HCB activates c-Src/HER1/STAT5b and
HER1/ERK1/2 signaling pathways and cell migration, in an
AhR dependent manner in MDA-MB-231 breast cancer cells