Gene interactions and pathways from curated databases and text-mining

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E2F2 — EPHB2

Text-mined interactions from Literome

Grewal et al., J Biol Chem 2001 : This transactivation resulted in the initiation of multiple cellular signals ( phosphorylation of the EGFRs and ERK and activation of cAMP-responsive element binding protein ( CREB ), NF-kappaB, and E2F ), as well as subsequent rapid down-regulation of cell-surface EGFRs and internalization and desensitization of the EGFRs without change in the total cellular complement of EGFRs
Fang et al., Cell Immunol 2009 : ERK1/2 activation leads to the release of E2F that could bind to the E2F binding sites in the inverted CCAAT box binding protein ( ICBP90 ) gene promoter
Paquin et al., BMC cell biology 2013 (Adenoma...) : Treatment of quiescent HIEC with serum induced ERK1/2 activation, E2F4 phosphorylation, E2F4 nuclear translocation and G1/S phase transition while inhibition of MEK/ERK signaling by U0126 prevented these events