◀ Back to MYC
MYC — PDCD2
Text-mined interactions from Literome
DuHadaway et al., Cancer Res 2001
(Cell Transformation, Neoplastic) :
In this study, we offer evidence that Bin1 participates in a mechanism through which
c-Myc activates
programmed cell death in transformed primary chick or rat cells
Luo et al., Blood 2005
(Leukemia, Myeloid, Acute) :
Ectopic expression of
c-Myc ( Myc ) in most primary cell types
results in
programmed cell death , and malignant transformation can not occur without additional mutations that block apoptosis
Inuzuka et al., Nature 2011
(Precursor T-Cell Lymphoblastic Leukemia-Lymphoma) :
In addition to accelerating cell growth, overexpression of Jun,
Myc or notch 1 can also
induce programmed cell death
Hoffman et al., Oncogene 1998
(Neoplasms) :
Inappropriate expression of
c-Myc under conditions which inhibit growth and down-regulate endogenous c-Myc expression, including serum deprivation and exposure to cytotoxic agents including the anticancer agents vinblastine, etoposide, Ara-C, and nocodazole, usually
results in
programmed cell death in many different cell types