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IFNG — NFKBIA

Text-mined interactions from Literome

Nomura et al., Life Sci 2001 : Experiments using stable clones of rat C6 glioma cells transfected with dominant negative IkappaB alpha ( serines 32 and 36 replaced by alanine ) suggest that NF-kappaB activation ( phosphorylation of IkappaB alpha ) is involved in LPS/IFNgamma- or IL-1beta/IFNgamma induced iNOS expression
Rahat et al., Int Immunol 2001 : Furthermore, IFN-gamma did not induce IkappaBalpha degradation
Komine et al., J Invest Dermatol 2005 : Degradation of inhibitor of nuclear factor kappa B ( IkappaB) alpha upon stimulation with IFNgamma and TNFalpha was not affected by the addition of RXM
Sheu et al., Food Chem Toxicol 2006 (Glomerulonephritis) : Moreover, addition of 100 microM CLA significantly diminished LPS-IFN-gamma induced protein degradation of inhibitor kappaB-alpha ( IkappaB-alpha ) and the protein expression of phosphorylated IkappaB-alpha in the cytosolic fraction as well as nuclear p65 expression ( P < 0.05 )
D'Alimonte et al., J Immunol 2007 : Moreover, guanosine abrogated IFN-gamma induced phosphorylation on Ser ( 727 ) and translocation of STAT-1alpha to the nucleus as well as TNF-alpha-/Abeta induced IkappaBalpha and NF-kappaB p65/RelA subunit phosphorylation, thus inhibiting NF-kappaB induced nuclear translocation
Song et al., Int J Mol Med 2007 : The molecular mechanism by which RAE inhibited iNOS gene expression appeared to involve the inhibition of NF-kappaB activation as a result of RAE 's suppression of IL-1beta and IFN-gamma induced IkappaBalpha degradation
Jiang et al., Eur J Haematol 2009 (Multiple Myeloma) : We also found that IFN-gamma and IL-6 can induce BLyS expression on MM cells, while after the treatment of BAY11-7082, an IkB-alpha phosphorylation inhibitor, IFN-gamma induced up regulation of BLyS was completely inhibited, suggesting that nuclear factor kappaB (NF-kappaB) might be involved in the mechanism of the regulation of BLyS levels in response to cytokines
Shultz et al., J Interferon Cytokine Res 2009 : In response to IFN-gamma , inhibitor of NF-kappaB (IkappaB) kinase beta ( IKK-beta ) is required to activate both newly synthesized IRF1 and the p65 subunit of NF-kappaB, which contributes to ip-10 expression by binding to kappaB sites in the ip-10 promoter, with little or no activation of classical NF-kappaB