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CDK5 — GSK3B

Pathways - manually collected, often from reviews:

• Reactome Reaction: CDK5 → GSK3B (reaction) Yoshimura et al., Cell 2005, Uchida et al., Genes Cells 2005, Schmidt et al., Adv Exp Med Biol 2007

Text-mined interactions from Literome

Parkitna et al., J Pharmacol Exp Ther 2006 : In conclusion, our data indicate that chronic morphine treatment activates a highly efficient pathway by means of which Cdk5 regulates GSK3beta activity
Lebel et al., Neuropharmacology 2009 : We demonstrate, using pharmacological tools, that PKA activation causes increase of calcium levels, leading to cyclin dependent kinase 5 activation by calpain proteolysis of p35 to p25 and glycogen synthase kinase 3beta activation by its phosphorylation at tyrosine 216