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IL12B — IL1R1
Text-mined interactions from Literome
Joosten et al., Ann Rheum Dis 2000
(Acute Disease...) :
Enhancement of IL10 and
IL1Ra by
anti-IL12 was confirmed in a tissue chamber model with SCW induced inflammation
Chieppa et al., J Immunol 2003
(Inflammation) :
MUC III ( a partially purified mucin ), biglycan ( a purified complex proteoglycan ), and mannosylated lipoarabinomannan from Mycobacterium tuberculosis affected cytokine production with high IL-10,
IL-1R antagonist, IL-1R type II, and
inhibition of
IL-12
Doisne et al., J Immunol 2011
:
In this study, we show that the concomitant presence of IL-1 and IL-23 is crucial to induce a rapid and sustained IL-17A/F and IL-22 response by these cells that requires TCR-CD1d interaction and partly relies on
IL-23 mediated upregulation of IL-23R and
IL-1R1 expression