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CDH2 — TCF20

Text-mined interactions from Literome

Gottardi et al., J Cell Biol 2004 : Beta-catenin plays essential roles in both cell-cell adhesion and Wnt signal transduction, but what precisely controls beta-catenin targeting to cadherin adhesive complexes, or T-cell factor ( TCF ) -transcriptional complexes is less well understood
Quasnichka et al., Circ Res 2006 (Vascular Diseases) : In summary, we have demonstrated that increasing N-cadherin and inhibiting beta-catenin/TCF signaling reduces VSMC proliferation, decreases the expression of cyclin D1 and increases levels of the cell cycle inhibitor, p21
Haÿ et al., Mol Cell Biol 2009 : N-cadherin overexpression in osteoblasts increases N-cadherin-LRP5 interaction, causing increased beta-catenin degradation and altered TCF/LEF transcription in response to Wnt3a ... Consistent with a functional mechanism, silencing N-cadherin expression in control cells increases TCF/LEF transcription and enhances the response to Wnt3a