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POU2F1 — SP1

Pathways - manually collected, often from reviews:

• FastForward regulation: SP1 → POU2F1 (transcriptional regulation, unknown)
  Evidence: DNABINDING
• NCI Pathway Database FOXA1 transcription factor network: SP1 (SP1) → Oct-1 (POU2F1) (transcription, activates) Eeckhoute et al., Genes Dev 2006
  Evidence: mutant phenotype, reporter gene, physical interaction

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: SP1 — POU2F1 (direct interaction, pull down) Lim et al., FEBS Lett 2009*
• IRef Biogrid Interaction: SP1 — POU2F1 (physical association, affinity chromatography technology) Lim et al., FEBS Lett 2009*
• IRef Biogrid Interaction: SP1 — POU2F1 (direct interaction, pull down) Ström et al., Nucleic Acids Res 1996*
• IRef Biogrid Interaction: SP1 — POU2F1 (direct interaction, two hybrid) Ström et al., Nucleic Acids Res 1996*
• IRef Biogrid Interaction: SP1 — POU2F1 (direct interaction, pull down) Gunther et al., Mol Cell Biochem 2000
• IRef Hprd Interaction: SP1 — POU2F1 (in vivo) Gunther et al., Mol Cell Biochem 2000, Lim et al., FEBS Lett 2009*, Ström et al., Nucleic Acids Res 1996*, Angeletti et al., J Virol 1998*
• IRef Hprd Interaction: SP1 — POU2F1 (two hybrid) Gunther et al., Mol Cell Biochem 2000, Lim et al., FEBS Lett 2009*, Ström et al., Nucleic Acids Res 1996*, Angeletti et al., J Virol 1998*
• IRef Hprd Interaction: SP1 — POU2F1 (in vitro) Gunther et al., Mol Cell Biochem 2000, Lim et al., FEBS Lett 2009*, Ström et al., Nucleic Acids Res 1996*, Angeletti et al., J Virol 1998*
• IRef Intact Interaction: SP1 — POU2F1 (physical association, two hybrid) Gunther et al., Mol Cell Biochem 2000
• IRef Intact Interaction: SP1 — POU2F1 (direct interaction, pull down) Lim et al., FEBS Lett 2009*
• IRef Intact Interaction: SP1 — POU2F1 (physical association, anti bait coimmunoprecipitation) Lim et al., FEBS Lett 2009*
• IRef Intact Interaction: SP1 — POU2F1 (physical association, anti tag coimmunoprecipitation) Lim et al., FEBS Lett 2009*
• IRef Intact Interaction: SP1 — POU2F1 (physical association, pull down) Gunther et al., Mol Cell Biochem 2000
• IRef Ophid Interaction: SP1 — POU2F1 (aggregation, confirmational text mining) Ström et al., Nucleic Acids Res 1996*
• IRef Ophid Interaction: SP1 — POU2F1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Liu et al., Eur J Biochem 2003 : Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3
Lim et al., FEBS Lett 2009 : O-GlcNAc modification of Sp1 inhibits the functional interaction between Sp1 and Oct1 ... Here we show that O-GlcNAc within the second serine/threonine-rich region of Sp1 interrupts a known interaction between Sp1 and Oct1 , and inhibits the cooperative activation of the U2 snRNA gene by Sp1 and Oct1