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CEBPA — VDR
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Song et al., Mol Endocrinol 2006
:
C/EBP-alpha at the composite element
plays an essential role in the
VDR regulation of SULT2A1, because 1 ) induction was lost for promoters with inactivating mutations at the VDRE or C/EBP element ; 2 ) SULT2A1 induction by 1,25- ( OH ) 2D3 in C/EBP-alpha-deficient cells required the expression of cotransfected C/EBP-alpha ; and 3 ) C/EBP-beta did not substitute for C/EBP-alpha in this regulation ... These results provide the first example of the essential
role of the interaction in cis between
C/EBP-alpha and VDR in directing 1,25- ( OH ) 2D3 induced expression of a
VDR target gene
Wood et al., Nutr Rev 2008
:
Recent studies, predominantly using the mouse 3T3-L1 pre-adipocyte cell culture model, have shown that the role of vitamin D in inhibiting adipogenesis is mediated at the molecular level through a
vitamin D receptor (VDR) dependent inhibition of
CCAAT enhancer binding protein-alpha ( C/EBP alpha ) and peroxisome proliferator activated receptor-gamma ( PPAR gamma ) expression and a decrease in PPAR gamma transactivating activity in the pre-adipocyte