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NUP43 — TGFB1
Text-mined interactions from Literome
Yamamoto et al., Eur J Biochem 1999
:
The rapid
activation of
p42/44 MAP kinase (MAPK) by
TGF-beta1 was eliminated completely, and transcriptional activation by TGF-beta1 of the plasminogen activator inhibitor-1 gene was reduced by 50 % in both endothelial cells and Mv1Lu when they were infected with AdCARasY57
Wenner et al., Braz J Med Biol Res 1999
(Cell Transformation, Neoplastic) :
TGF-beta 1 delayed EGF- or PDGF induced cyclin D1 expression and
blocked the induction of active
p42/p44MAPK ... The mechanism by which
TGF-beta 1 induces a block in
p42/p44MAPK activation is being examined and the possibility that TGF-beta 1 regulates phosphatase activity is being tested
Bamba et al., Am J Physiol Gastrointest Liver Physiol 2003
:
IL-1beta and
TGF-beta1 induced an activation of ERK
p42/44 and p38 MAP kinases, and the MAP kinase inhibitors ( SB-202190, PD-98059, and U-0216 ) significantly reduced the IL-1beta- and TGF-beta1 induced IL-11 secretion
Sohn et al., Kidney Int 2005
:
Inhibition of p38 ( mapk ) or
p42/44(mapk) activities did not
affect LDL induced
TGF-beta1 , CTGF, and collagen I expression, whereas inhibition of c-Jun NH2-terminal kinase (JNK) suppressed LDL induced TGF-beta, CTGF, and collagen I expression
Kanno et al., Horm Metab Res 2005
(MAP Kinase Signaling System) :
We previously reported that
transforming growth factor-beta ( TGF-beta )
activates p44/p42 mitogen activated protein ( MAP ) kinase and p38 MAP kinase, resulting in the stimulation of vascular endothelial growth factor ( VEGF ) synthesis in osteoblast-like MC3T3-E1 cells
Gui et al., Dig Dis Sci 2007
:
Furthermore, emodin markedly inhibited
TGFbeta1 induced
p42/p44 mitogen activated protein kinase phosphorylation but did not alter PMA induction
Vásquez et al., J Cell Physiol 2007
:
TGF-beta1 , via TGF-beta receptors I (TbetaRI) and TbetaRII,
activates Smad2 and mitogen activated protein kinases p44 and
p42 ( p42/44(mapk) ) ...
TGF-beta1 and high D-glucose
increased p42/44(mapk) and Smad2 phosphorylation, an effect blocked by PD-98059 ( MEK1/2 inhibitor )
Reimann et al., FEBS Lett 1997
:
In this paper we show that in cultured hepatic stellate cells
TGF-beta1 induces activation of Ras, Raf-1, MEK and MAPK
p42 and p44
Axmann et al., Biochem Biophys Res Commun 1998
:
TGF-beta1 rapidly
induced the activation of c-Raf-1, MEK-1, and MAPK
p42 and p44