Gene interactions and pathways from curated databases and text-mining

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HPT — PTX3

Text-mined interactions from Literome

Juergensen et al., Adv Perit Dial 1998 (Hyperparathyroidism, Secondary...) : We reviewed New Haven CAPD unit patients who failed medical therapy and required parathyroidectomy ( PTX ) for control of severe HPT [ sustained immunoreactive parathyroid hormone ( iPTH ) level > 600 pg/mL ]
Decker et al., World J Surg 2001 (Hyperparathyroidism, Secondary...) : Despite advances in dialysis technique and pharmacologic therapy, there has been no change in the proportion of dialysis patients requiring PTX for 2HPT or 3HPT
Jofré et al., Kidney Int Suppl 2003 (Hyperparathyroidism, Secondary...) : Hyperparathyroidism (HPT) is common in patients on dialysis, and parathyroidectomy ( PTx ) is often required
Tominaga et al., Clinical calcium 2008 (Hyperparathyroidism) : Parathyroidectomy ( PTX ) can control both primary and renal hyperparathyroidism (HPT) in almost all cases, however surgeons hesitate the operation for patients who belong to high risk group and have the possibility of severe complications, ie bilateral palsy of recurrent laryngeal nerves
Jean et al., Nephrol Ther 2012 (Hyperparathyroidism, Secondary) : From this population, we identified five main types of HPT : ( 1 ) HPT with ` no bone impact ' had normal or low bone marker levels ( n=28, 17.7 % ) ; ( 2 ) ` secondary ' HPT had elevated bone marker levels, but showed favorable response to CT ( n=59, 37.7 % ) ; ( 3 ) ` tertiary ' HPT was accompanied with hypercalcemia and required CC or PTX in case of CT failure ( n=11, 6.9 % ) ; ( 4 ) ` mixed ' HPT could not be completely treated with CT and required CC or PTX ( n=57, 36 % ) ; ( 5 ) ` resistant ' HPT did not show hypercalcemia, but required PTX after CT and CC failure ( n=3, 1.8 % )