◀ Back to IFNG

IFNG — MMP2

Text-mined interactions from Literome

Orucevic et al., Int J Cancer 1999 (Adenocarcinoma...) : In addition, there was up-regulation of MMP-2 , when extra NO was induced by IFN-gamma and LPS
Nold et al., Naunyn Schmiedebergs Arch Pharmacol 2003 : Whereas IL-18 and TNFalpha induced the protease, MMP-9 release was not mediated by IFNgamma
Martelli-Junior et al., J Periodontol 2003 (Fibromatosis, Gingival) : IFN-gamma reduced both type I collagen and Hsp47 expression, whereas it had a slight effect on the expression of MMP-1 and MMP-2
Makino et al., Cell Immunol 2005 (Leprosy) : The DC-mediated IFN-gamma production was dependent on the expression of MHC, CD86, and MMP-II antigens
Ben-Hur et al., J Neuroimmunol 2006 : NPCs ' gelatinase activities of MMP-2 and MMP-9, as determined by zymography, were increased by TNF-alpha, and to a lesser extent by IFN-gamma
Xue et al., Zhonghua Bing Li Xue Za Zhi 2007 : [ Effect of interferon-gamma on transforming growth factor beta/Smad signal pathway and expression of matrix metalloproteinase-2 and tissue inhibitors of matrix metalloproteinase-2 in cultured rat mesangial cells ]
Alvarado et al., Cytokine 2008 : In this report, the effects of the bacterial lipopolysaccharide (LPS) and ECM bound IFN-gamma on MT1-MMP expression and MMP-2 activity were evaluated by Western blot, RT-PCR and zymography in isolated intestinal epithelial and cultured HT-29 cells ... In addition, the active form of MMP-2 was also decreased in the presence of both LPS and IFN-gamma , indicating that lower MMP-2 activity accompanied the decrease in MT1-MMP expression
Wang et al., World J Gastroenterol 2008 (Liver Cirrhosis) : Both Cpd 861 and IFN-gamma reduced the mRNA levels of collagen type III, MMP-2 and TGF-beta1
Nareika et al., Atherosclerosis 2009 (Atherosclerosis...) : Results showed that high glucose and IFN gamma had a synergistic effect on the expression of MMP-1, MMP-9 and IL-1 beta
Mann et al., Ann Otol Rhinol Laryngol 1995 (Carcinoma, Squamous Cell...) : Supernatants of HNSCC cell lines SCC-25 and FADU stimulated with interleukin (IL)-1 alpha and IL-1 beta demonstrated modest induction of 92 kd GL production by zymogram analysis when compared with controls ; IL-2, IL-6, and interferon-gamma had no consistent effect on MMP production
Varga et al., Adv Exp Med Biol 1996 : Supplementation with tryptophan completely overcame the inhibitory effects of interferon-gamma on MMP mRNA expression and metalloproteinase secretion into the media ... These results indicate that oxidative tryptophan metabolism mediates the effects of interferon-gamma on MMP gene expression in human fibroblasts
Wu et al., J Cell Physiol 1997 (Sjogren's Syndrome) : This study examined the role of IFN-gamma and ( + ) TNF-alpha in the regulation of the matrix metalloproteinases, MMP-2 ( 72 kD gelatinase A ) and MMP-9 ( 92 kD gelatinase B )