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CLDN2 — RHOA
Text-mined interactions from Literome
Bruewer et al., Am J Physiol Cell Physiol 2004
:
All CA GTPases increased the detergent solubility of claudins-1 and -2, but CA
RhoA alone
reduced claudin-2 and ZO-1 partitioning to detergent-insoluble membrane rafts
Guillemot et al., PloS one 2013
:
These results and previous studies suggest a model whereby cingulin and paracingulin redundantly control the expression of specific TJ proteins through distinct GATA-4- and RhoA dependent mechanisms, and that in the absence of sufficient levels of GATA-4 the
RhoA mediated upregulation of
claudin-2 is inhibited