◀ Back to TP53

NFKBIA — TP53

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: NFKBIA — TP53 (physical association, affinity chromatography technology) Chang et al., J Biol Chem 2002*
• IRef Biogrid Interaction: NFKBIA — TP53 (direct interaction, two hybrid) Chang et al., J Biol Chem 2002*
• IRef Hprd Interaction: TP53 — NFKBIA (two hybrid) Chang et al., J Biol Chem 2002*
• IRef Hprd Interaction: TP53 — NFKBIA (in vivo) Chang et al., J Biol Chem 2002*
• IRef Ophid Interaction: NFKBIA — TP53 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Shao et al., Oncogene 2000 (Adenocarcinoma...) : Transduced wt-p53 expression increased the cytoplasmic expression of I kappaB alpha as well as its binding ability to NF-kappaB, thus markedly reducing the amount of NF-kappaB that translocated to the nucleus
Pise-Masison et al., AIDS Res Hum Retroviruses 2000 : Consistent with these results, expression of the I-kappaBalpha ( S32,36A ) mutant that blocks NF-kappaB activation blocks Tax mediated p53 inhibition
Fujioka et al., J Biol Chem 2004 : Importantly, lack of RelA, IKK, and p53 as well as expression of a dominant negative IkappaBalpha ( IkappaBalphaM ) inhibited NF-kappaB dependent p53 activation and apoptosis
Li et al., World J Gastroenterol 2006 : Effects of IkappaBalpha and its mutants on NF-kappaB and p53 signaling pathways ... Effects of IkappaBalpha and its mutants on the transprition level of NF-kappaB, NF-kappaB downstream target gene TNF-alpha, p53 and p53 downstream target gene Bax were observed by real time QT-PCR