Gene interactions and pathways from curated databases and text-mining

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AHSA1 — HMOX1

Text-mined interactions from Literome

Chen et al., Cell Mol Biol Incl Cyto Enzymol 2000 : ERK and p38 inhibitors also suppressed induction of HO-1 by SNAP and GSNO
Liu et al., Oncogene 2004 (Stomach Neoplasms) : The levels of HO-1 and p21 induced were significantly inhibited by p38 mitogen activated protein kinase ( p38 MAPK ) inhibitor ( SB203580 ) and extracellular regulated kinase (ERK) inhibitor ( PD098059 )
Ricchetti et al., J Leukoc Biol 2004 (Inflammation) : IL-10 induced expression of HO-1 required the activation of signal transducer and activator of transcription ( STAT ) -3 but not p38 mitogen activated protein kinase
Chen et al., J Cell Biochem 2004 (Carcinoma, Papillary...) : The induced levels of HO-1 and p21 were significantly reduced by p38 mitogen activated protein kinase ( p38 MAPK ) and extracellular regulated kinase (ERK) inhibitors
Foresti et al., J Pharmacol Exp Ther 2005 : By using different mitogen activated protein kinase inhibitors, we determined that the extracellular signal regulated kinase, p38 , and c-Jun NH ( 2 ) -terminal protein kinase pathways play only a minor role in the induction of HO-1 by rosolic acid and 2'-hydroxychalcone
Yang et al., Free Radic Biol Med 2008 (Lymphoma) : Gallium induced Nrf-2 activation and HO-1 expression were diminished by a p38 MAP kinase inhibitor
Guan et al., J Cell Biochem 2008 (MAP Kinase Signaling System) : Increased phospho p38 activity precedes and likely mediates HO-1 induction by EA. Increased AP-1 binding may underlie the transcriptional regulation of HO-1 by EA
Naidu et al., J Immunol 2009 : In the present study, it is demonstrated that pharmacological inhibitors of p38 induced HO-1 expression in monocytic cells ... Accordingly, inhibitors of p38 induced binding of nuclear proteins to a Nrf2 target sequence of the HO-1 promoter, but did not affect HO-1 protein expression and promoter activity in Nrf2 ( -/- ) MEF
Lee et al., J Cell Biochem 2011 (MAP Kinase Signaling System) : Fisetin induces Nrf2 mediated HO-1 expression through PKC-d and p38 in human umbilical vein endothelial cells
Liang et al., Mol Cell Biochem 2011 : The pharmacological inhibition of cJun-N-terminal kinases ( JNKs ) blocked the DMSO induced HO-1 up-regulation, while inhibition of extracellular regulated kinase and p38-MAPK did not block heme oxygenase-1 up-regulation
Mouawad et al., PloS one 2013 : Induction of HO-1 by statins was dependent on p-38 MAP kinase activation in all types of macrophages