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AHSA1 — HMOX1
Text-mined interactions from Literome
Chen et al., Cell Mol Biol Incl Cyto Enzymol 2000
:
ERK and
p38 inhibitors also
suppressed induction of
HO-1 by SNAP and GSNO
Liu et al., Oncogene 2004
(Stomach Neoplasms) :
The levels of
HO-1 and p21 induced were significantly
inhibited by
p38 mitogen activated protein kinase ( p38 MAPK ) inhibitor ( SB203580 ) and extracellular regulated kinase (ERK) inhibitor ( PD098059 )
Ricchetti et al., J Leukoc Biol 2004
(Inflammation) :
IL-10 induced expression of
HO-1 required the activation of signal transducer and activator of transcription ( STAT ) -3 but not
p38 mitogen activated protein kinase
Chen et al., J Cell Biochem 2004
(Carcinoma, Papillary...) :
The induced levels of
HO-1 and p21 were significantly
reduced by
p38 mitogen activated protein kinase ( p38 MAPK ) and extracellular regulated kinase (ERK) inhibitors
Foresti et al., J Pharmacol Exp Ther 2005
:
By using different mitogen activated protein kinase inhibitors, we determined that the extracellular signal regulated kinase,
p38 , and c-Jun NH ( 2 ) -terminal protein kinase pathways
play only a minor role in the induction of
HO-1 by rosolic acid and 2'-hydroxychalcone
Yang et al., Free Radic Biol Med 2008
(Lymphoma) :
Gallium induced Nrf-2 activation and
HO-1 expression were
diminished by a
p38 MAP kinase inhibitor
Guan et al., J Cell Biochem 2008
(MAP Kinase Signaling System) :
Increased phospho
p38 activity precedes and likely
mediates HO-1 induction by EA. Increased AP-1 binding may underlie the transcriptional regulation of HO-1 by EA
Naidu et al., J Immunol 2009
:
In the present study, it is demonstrated that pharmacological inhibitors of
p38 induced
HO-1 expression in monocytic cells ... Accordingly, inhibitors of
p38 induced binding of nuclear proteins to a Nrf2 target sequence of the HO-1 promoter, but did not
affect HO-1 protein expression and promoter activity in Nrf2 ( -/- ) MEF
Lee et al., J Cell Biochem 2011
(MAP Kinase Signaling System) :
Fisetin
induces Nrf2 mediated
HO-1 expression through PKC-d and
p38 in human umbilical vein endothelial cells
Liang et al., Mol Cell Biochem 2011
:
The pharmacological inhibition of cJun-N-terminal kinases ( JNKs ) blocked the DMSO induced HO-1 up-regulation, while inhibition of extracellular regulated kinase and
p38-MAPK did not
block heme oxygenase-1 up-regulation
Mouawad et al., PloS one 2013
:
Induction of
HO-1 by statins was
dependent on
p-38 MAP kinase activation in all types of macrophages